Jacob's Cure is a non-profit organization founded by Jordana Holovach to save her son, Jacob, who was diagnosed with

Canavan Disease, a rare genetic neurological disorder,

at six months old. Children with Canavan Disease become trapped in their bodies, develop seizures, lose their ability to see and swallow, and die in the first decade of life. The research funded by Jacob's Cure has slowed or halted the progression of the disease in most of the children who received gene therapy and have begun the recommended pharmacological treatments. While there is currently no cure for Canavan Disease, Jacob's Cure is funding a stem cell clinical trial that aims to further treat and ultimately cure Canavan disease. This stem cell research may very well revolutionize the manner in which "white matter" neurological diseases, such as Parkinson's, MS and ALS, are treated and will be a model for their cure.
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